整合nociplastic疼痛到神经病痛框架:一个修订分类的提案
1Department of Orthopedic Surgery, Yamaguchi Heisei Hospital, Iwakuni, Yamaguchi Prefecture, Japan.
Frontiers in pain research (Lausanne, Switzerland)
|November 17, 2025
概括
诺基普拉斯痛 (NpP) 的诊断和治疗仍然具有挑战性,因为它与神经病痛 (NeP) 重叠. 建议将NPP整合到NeP中,以简化临床实践并改善各种疼痛疾病的患者护理.
科学领域:
- 疼痛研究和临床疼痛管理.
背景情况:
- 国际疼痛研究协会 (IASP) 将疼痛分为感觉性,神经性 (NeP) 和感觉性 (NpP) 类型.
- 从临床上来说,区分NPP与NeP是具有挑战性的,因为它们具有共同的症状,如疼痛过敏和自发疼痛.
- 目前对NPP缺乏诊断方法和治疗指南,导致研究和实践的不确定性.
研究的目的:
- 为了解决围绕诺基普拉斯痛 (NpP) 的诊断和治疗模两可.
- 提出临时计划,简化NPP的分类和管理,旨在改善患者护理.
主要方法:
- 审查现有的疼痛分类系统,特别是IASP的类别.
- 分析诺基普拉斯痛 (NpP) 及其与神经病痛 (NeP) 重叠所带来的诊断和治疗挑战.
- 制定四个临时计划,将NpP整合到NeP中,或将其分类为NeP.
主要成果:
- 关于 NeP 和 NpP 的定义和概念化,学术上存在显著的模两可.
- 现有的问卷不足以可靠地区分NPP和NeP.
- 提出四个临时计划来管理NPP,建议将NPP整合到NeP (使用NeP术语) 是推的方法.
结论:
- 诺西普拉斯疼痛 (NpP) 的概念化在疼痛研究和临床实践中造成了相当大的不确定性.
- 建议通过将NPP整合到NeP来简化分类,以提高诊断清晰度和治疗策略.
- 拟议的计划旨在为更好地理解和管理疼痛做出贡献.
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