在经过治疗的细菌病症数月后,与Haemophilus influenzae相关的真菌性动脉瘤
Josiah Bennett1, Sarah Lohsen2, Elizabeth Y Kim2
1Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
ASM case reports
|November 17, 2025
概括
侵袭性非类型性Haemophilus influenzae (NTHi) 感染,特别是在艾滋病毒感染的男性中,正在增加. 最近的一例突出显示,NTHi导致罕见的伪动脉瘤,表明疾病呈现正在演变.
科学领域:
- 传染性疾病 传染性疾病
- 细菌学 细菌学是一门学科.
- 艾滋病毒 医学 艾滋病毒 医学
背景情况:
- 在亚特兰大,2017-2018年期间,侵袭性非类型性Haemophilus influenzae (NTHi) 感染在亚特兰大显著增加.
- 大多数NTHi分离物来自两个相关的遗传系,这表明在HIV感染者的网络中传播.
研究的目的:
- 报告一个罕见的NTHi感染病例,呈现为HIV患者的伪动脉瘤.
- 突出与致病性NTHi菌株相关的新型疾病表型的出现.
主要方法:
- 案例报告的呈现方式.
- 对NTHi分离物的鉴定和遗传谱系分析.
主要成果:
- 一名63岁的男性,艾滋病毒控制良好,出现NTHi细菌病和心膜炎.
- 该患者被诊断出患有感染的右侧表面大腿动脉伪动脉瘤,由NTHi菌株引起,该菌株属于与最近病例集群相关的血统.
结论:
- 这一案例表明,特别致命的NTHi菌株可以引起异常和严重的感染.
- 这些发现强调了识别不断演变的NTHi疾病表现的重要性,特别是在免疫受损人群中.
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