中部膝关节骨关节炎中的Varus变形与下肢肌肉的脂肪退化相关:基于人工智能的计算机断层扫描分析
Minami Suzuki1, Tomofumi Kinoshita1, Kohei Kono1
1Department of Orthopaedic Surgery Ehime University Graduate School of Medicine Toon Ehime Japan.
Journal of experimental orthopaedics
|November 17, 2025
概括
在中膝关节骨关节炎 (KOA) 中的Varus变形与干部,部和下腿肌肉的脂肪退化有关,而不仅仅是肌肉体积的损失. 这一发现凸显了KOA进展如何影响整个四肢的肌肉.
科学领域:
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
- 肌肉生理学 肌肉生理学
背景情况:
- 膝关节骨关节炎 (KOA) 的进展导致下肢不整齐,影响日常活动.
- 不对齐对肌肉缩和从干部到脚部的退化在KOA的具体影响尚不清楚.
研究的目的:
- 为了研究形变形对肌肉体积和脂肪退化在中位KOA患者的影响.
- 为了评估肌肉变化从干部到脚与形变形的关系.
主要方法:
- 包括79名末期中位KOA患者.
- 使用从站立的X射线图中获得的关节膝关节 (HKA) 角度来量化Varus变形.
- 用10个肌肉群的AI细分CT图像来评估肌肉体积和脂肪退化.
主要成果:
- 发现形变形 (HKA) 与部最大,部中/小,肌,四头肌和下腿后部部位的脂肪退化增加之间存在显著的关联.
- 在HKA和肌肉体积之间没有观察到显著的相关性.
结论:
- 介质KOA中的Varus变形与整个下肢和干部肌肉的脂肪退化有关,而不是减少肌肉体积.
- KOA的进展显著影响了膝关节本身以外的肌肉健康.
相关概念视频
01:23Knee Joint
3.1K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
3.1K
01:16Bones of the Lower Limb: Femur and Patella
4.8K
The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...
4.8K