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Updated: Jan 11, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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以LRRK2为媒介的NLRC4酸化对IL-1β/IL-18分泌的不同调节

Sharmina Deloer1, Ivan Fuss1, Portia Gough2

  • 1Mucosal Immunology Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD, United States.

Frontiers in immunology
|November 17, 2025
PubMed
概括

LRRK2-激酶酸化调节NLRC4炎症体,影响IL-1β的产生和肠道屏障功能. 在克罗恩病中抑制LRRK2-激酶.

关键词:
克罗恩氏病是什么 克罗恩氏病是什么这是LRRK2在NLRC4中,一些炎症一些炎症这是一种炎症炎症炎症炎症.

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