预防性抗生素在局部麻醉下超腺超声波导向前列腺活检中的使用:一项回顾性观察性研究
Anurag Agarwal1, Katherine V Rhodes1, Daniel Grogan1
1General Surgery, Betsi Cadwaladr University Health Board, Bangor, GBR.
Cureus
|November 17, 2025
概括
对于横前列腺活检,跳过抗生素是安全的,不会增加感染风险. 然而,吸烟与手术后尿路感染的可能性更高有关.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 预防性抗生素是跨关节前列腺活检 (LATP) 的标准,尽管感染风险低.
- 这项研究调查了在LATP期间使用和不使用抗生素预防的感染率.
研究的目的:
- 评估在LATP中省略预防性抗生素的安全性和有效性.
- 为了确定活检后感染的危险因素.
主要方法:
- 对接受LATP治疗的186名患者进行了回顾性分析.
- 在接受预防性抗生素 (n=91) 和未接受预防性抗生素 (n=95) 的患者之间比较感染结果.
- 主要结局:30天内尿路感染 (UTI);次要结局:因感染而入院.
主要成果:
- 在两组中,活检后尿路感染的发病率较低,没有显著差异.
- 没有败血症病例或因感染入院患者的显著增加.
- 吸烟史与尿路感染风险增加显著相关 (p < 0.05).
结论:
- 在LATP中省略预防性抗生素是安全的,不会增加感染风险.
- 吸烟是活检后尿路感染的一个重要危险因素.
- 选择性抗生素使用可以提高抗菌药物管理,而不会影响患者的安全.
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