甲状腺病变中的贝塞斯达类别与组织病理学的相关性:一个单一的三级护理中心经验
Sreenidhi Sreeram1, Leena Dennis Joseph1, Subalakshmi Balasubramanian1
1Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|November 17, 2025
概括
这项研究发现甲状腺结节的恶性瘤风险高于预期. 改进精细针吸收细胞学 (FNAC) 技术和报告标准可以提高甲状腺病变的诊断准确性.
科学领域:
- 内分泌学 在内分泌学.
- 细胞病理学 细胞病理学
- 在瘤学瘤学.
背景情况:
- 甲状腺结节很常见,但评估恶性瘤风险是具有挑战性的.
- 三重评估包括临床检查,成像 (TIRADS) 和FNAC是标准的.
- 2023年贝塞斯达甲状腺细胞学报告系统 (TBSRTC) 将FNAC风险分层.
研究的目的:
- 为了比较甲状腺组织病理学与FNAC细胞学结果.
- 通过使用TBSRTC类别来评估FNAC的表现.
- 评估每个TBSRTC类别的恶性瘤 (RoM) 风险.
主要方法:
- 对101个甲状腺组织病理病例进行了回顾性横截面研究.
- 与TBSRTC分类的相应FNAC涂抹的相关性.
- 计算灵敏度,特异性和 RoM 的计算.
主要成果:
- 65.35%是良性的,35.64%是恶性的;乳头甲状腺癌是最常见的 (83%的恶性瘤).
- 贝塞斯达II类的RoM高于既定率 (18%).
- 第四类 (卵泡瘤) 显示不一致性和更高的RoM (50%).
- 研究的灵敏度为68.57%.
结论:
- 该研究观察到RoM比以前发表的更高.
- 改进FNAC技术和标准化报告标准可以提高诊断准确性.
- 像免疫细胞化学和分子测试这样的辅助方法可能有助于不确定的病变.
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