面区域的骨化纤维瘤:一个诊断上具有挑战性的病例报告
Jay M Patel1, Samir Joshi1, Sudhir Pawar1
1Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Pune, IND.
Cureus
|November 17, 2025
概括
良性纤维骨性病变,如骨化纤维瘤 (COF),可能很难诊断. 手术切除是COF推的治疗方法,确保患者获得最佳的治疗结果.
科学领域:
- 口腔和面病理学 口腔和面病理学
- 骨生物学 骨生物学
- 新生病新发性疾病
背景情况:
- 良性纤维骨性病变是一组疾病,其特点是正常骨被矿化纤维结合组织所取代.
- 常见的类型包括纤维发育不良症,骨化纤维瘤和骨性发育不良症,经常呈现重叠的特征,使诊断复杂化.
- 水泥骨化纤维瘤 (COF) 是一种中枢性瘤,起源于介质细胞,分化为骨和骨,目前关于其分类和诊断标准的争论仍在进行中.
研究的目的:
- 介绍一个被诊断患有骨化纤维瘤 (COF) 的病例研究.
- 突出与良性纤维骨性病变相关的诊断挑战.
- 强调外科切除作为COF的主要治疗方法的疗效.
主要方法:
- 一位患者在右下出现了无痛的,扩张性的胀.
- 诊断程序包括临床检查,放射学评估和组织病理学确认.
- 治疗包括手术切除病变.
主要成果:
- 组织病理学检查证实了水泥骨化纤维瘤 (COF) 的诊断.
- 患者接受了下病变的外科切除.
- 该案例说明了COF的典型呈现和管理.
结论:
- 水泥骨化纤维瘤 (COF) 是良性纤维骨性病变中的一个独特实体,需要准确的诊断.
- 整体手术切除被认为是COF的黄金标准治疗方法,导致最佳结果.
- 这一案例凸显了基因病理学确认在纤维骨性病变治疗决策指导中的重要性.
相关概念视频
Sutures of the Skull
10.0K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
10.0K
Bone Formation by Intramembranous Ossification
10.1K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
10.1K
Cranial Bones: Superior and Posterior View
4.8K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
4.8K
Cranial Bones: Lateral View
4.3K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
4.3K
Cranial and Spinal Meninges
3.5K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
3.5K
Osteoclasts in Bone Remodeling
3.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.9K


