伤寒热的临床谱和结果:一项回顾性研究
Zeeshan Shafqat1, Saadia Kanwal1, Abdullah Yousaf2
1Internal Medicine, Shalamar Hospital, Lahore, PAK.
Cureus
|November 17, 2025
概括
伤寒热严重影响年轻人,呈现各种症状和潜在的并发症. 虽然大多数患者都会康复,但肠道穿孔和败血症导致了显著的发病率和死亡率.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 伤寒热在流行地区是一个关键的全球健康问题.
- 它导致大量的疾病和死亡,具有不同的临床表现.
研究的目的:
- 调查伤寒热的临床特征,并发症和患者结果.
- 提供有关台风热在特定地区的影响的见解.
主要方法:
- 巴基斯坦拉合尔Shalamar医院305例确诊的伤寒病例的回顾性分析 (2022年4月至2025年4月).
- 数据收集包括人口统计,症状,实验室结果,并发症,治疗方法和结果.
- 通过血液培养或血清学测试证实了诊断.
主要成果:
- 研究人口的平均年龄为22.6岁,男性与女性的比例为1.4:1.
- 常见的症状包括发烧 (100%),腹痛 (62%),食欲丧失 (43.3%) 和头痛 (40.3%).
- 在64.3%的阳性血液培养 (总体78.0%) 中发现了沙门氏菌Typhi. 胃肠道出血 (10.5%) 和肠道穿孔 (6.9%) 等并发症影响了27.5%的患者.
结论:
- 伤寒热不成比例地影响年轻人,表现出广泛的临床症状.
- 尽管康复率高 (94.1%),但诸如穿孔和败血症等并发症导致显著的发病率和死亡率 (2.9%).
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