使用超声波提取的Lavandula Angustifolia聚糖的酸化:特征,抗氧化剂和低血糖活性
Qingze Gu1, Jiamin Wan1, Junlong Wang1
1School of Chemistry and Chemical Engineering, Xinjiang Key Laboratory of Lavender Conservation and Utilization and Xinjiang Key Laboratory of Natural Products Chemistry and Application in Universities and Colleges, Yili Normal University, Yining, P. R. China.
Journal of food science
|November 17, 2025
概括
超声波辅助提取优化了Lavandula angustifolia多糖 (LAP) 的产量和活性. 酸化增强了LAP的作用.
科学领域:
- 生物化学 生化学
- 药理学 药理学是指药理学的学科.
- 食品科学 食品科学 食品科学
背景情况:
- 拉文杜拉 (Lavandula angustifolia) 具有重要的药用和食用特性.
- 来自Lavandula angustifolia (LAP) 的多糖因其生物活性引起人们的兴趣.
- 提取和修改方法可以影响多糖的产量和有效性.
研究的目的:
- 使用不同的方法,优化拉万杜拉 (Lavandula angustifolia) 多糖的提取.
- 研究酸化修饰对LAP特性和活动的影响.
- 评估修改LAP的抗氧化和抗高血糖潜力.
主要方法:
- 使用了超声辅助提取 (UAE),微波辅助提取 (MAE) 和热水提取 (HWE).
- LAP被分离,净化,然后被酸化以产生衍生物 (PLAP1-3).
- 评估了物理化学性质,结构特征,抗氧化剂和抗高血糖活性.
主要成果:
- 在300W阿联获得最佳的LAP提取,产量为21.51%,具有显著的DPPH基因清除 (56.76%) 和α-氨酶抑制 (49.95%).
- 酸化修饰得到证实,增强了抗氧化和抗高血糖活性.
- PLAP2 (DS 1.58) 在体外表现出强大的抗氧化活性,并有效抑制α-氨酶和α-葡萄糖酶,改善胰岛素抵抗细胞的葡萄糖吸收.
结论:
- 在300W的阿联是 LAP 提取最有效的方法.
- 酸化显著增强了LAP的抗氧化和抗高血糖特性.
- 改性LAP,特别是PLAP2,显示出作为一种功能成分的承诺,用于管理氧化应激和高血糖症.
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