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Updated: Jan 11, 2026

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
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协同作用但在临床上是不可实现的:阿莫西西林/塞夫特里亚克松组合对抗对安比西林敏感的Enterococcus faecium

Ahmed Ashrin1, Clémence Hagenimana1,2, Hervé Jacquier1,2

  • 1Unité de Bactériologie, Département de Prévention, Diagnostic et Traitement des Infections, Hôpitaux Universitaires Henri Mondor-Albert Chenevier, Assistance Publique-Hôpitaux de Paris (AP-HP), Créteil 94010, France.

The Journal of antimicrobial chemotherapy
|November 17, 2025
PubMed
概括

阿莫西西林/塞夫特里亚克森组合在实验室中显示出对安比西林敏感的Enterococcus faecium (EFM-S) 的协同作用,但对传染性内心炎 (IE) 临床上无关紧要. 这表明,由于无法达到药物度,因此排除了E. faecium感染的治疗方案.

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