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Updated: Jun 28, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
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用人类角膜上皮细胞共培模型分辨眼部致病性葡萄球菌表皮球菌分离物.

Qiankun Chen1, Yuan Wei1, Jinding Pang1

  • 1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, China.

Translational vision science & technology
|November 17, 2025
PubMed
概括

这项研究开发了一种体外人类角膜上皮细胞 (HCEC) 培养模型,以区分致病性和非致病性Staphylococcus epidermidis. HCEC检测准确预测细菌病原性,有助于诊断细菌角膜炎.

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Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...