自闭症中的:在大型住院精神病患者样本中的患病率和相关因素
Kate Kielty1, Kexin Luo2, Matthew Siegel3,4
1Division of Child Neurology, Department of Pediatrics, University of Pittsburgh School of Medicine, 4401 Penn Ave, Pittsburgh, PA, 15224, USA. kieltyk@upmc.edu.
Journal of autism and developmental disorders
|November 17, 2025
概括
影响了近19%的自闭症青少年在精神病学环境中,与较低的智商和更多的遗传测试有关. 这些发现有助于临床医生照顾患有同时发生的自闭症患者.
科学领域:
- 神经发育障碍 神经发育障碍
- 儿童和青少年精神病学
- 临床神经学 临床神经学
背景情况:
- 自闭症谱系障碍 (ASD) 和经常同时发生,报告的患病率范围广泛从2.4%到46%.
- 了解这种并发症至关重要,尤其是在专门的精神病学环境中,这些人群经常接受治疗.
研究的目的:
- 为了研究和自闭症之间的关系,在精神病医院住院的青年队伍中.
- 在这个代表性不足的人群中识别与相关的因素.
主要方法:
- 分析来自自闭症住院患者收集的数据 (N=1354,年龄为4-21岁) 青少年确诊ASD.
- 利用t测试和千平方测试来比较患有和没有的自闭症个体,以人口,临床和遗传变量为依据.
主要成果:
- 症在18.9%的研究参与者中存在.
- 与年龄较大,非语言智商较低和深度自闭症特征有显著的关联.
- 基因检测率的增加,发作/头痛的家族史,以及更高的药物计数与有关.
结论:
- 这项研究复制了精神病住院患者青年队伍中和自闭症之间的已知关联.
- 在患有的自闭症个体中发现了新的关联,包括增加遗传检测和药物负担.
- 这些发现可以指导在精神病医院治疗的自闭症青少年的临床护理和家庭咨询.
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