对决策分析建模方法在创伤后应激障碍治疗的经济评估中的系统审查
Sheradyn R Matthews1, Laura C Edney2, Reginald D V Nixon3
1College of Education, Psychology and Social Work, Flinders Institute for Mental Health and Wellbeing, Flinders University, G.P.O. Box 2100, Adelaide, SA, 5001, Australia. sheradyn.matthews@flinders.edu.au.
PharmacoEconomics
|November 17, 2025
概括
这次审查发现,创伤后应激障碍 (PTSD) 治疗的经济模型是如何构建的,以及它们使用什么数据的,存在显著差异. 未来的研究应该旨在对PTSD干预措施进行更一致的经济评估.
科学领域:
- 卫生经济学 卫生经济学
- 精神病学是一个精神病学.
- 决策科学 决策科学 决策科学
背景情况:
- 创伤后应激障碍 (PTSD) 严重影响日常功能.
- 经济评估对于比较PTSD治疗和指导实施至关重要.
- 现有的基于PTSD治疗的基于模型的经济评估显示了方法和参数的变化.
研究的目的:
- 系统地审查PTSD治疗的经济评估中的模型结构和参数输入.
- 确定用于PTSD治疗经济评估的决策分析模型的变化.
主要方法:
- 在多个数据库 (MEDLINE,PsycINFO,SCOPUS等) 进行了系统的文献搜索. 从2000年开始到2025年.
- 包括使用决策分析模型对PTSD治疗进行全面经济评估的研究.
- 提取了模型结构和参数的数据,并进行了质量评估.
主要成果:
- 确定了14项基于模型的研究,使用决策树,马尔科夫模型,组合方法和基于代理的模型.
- 观察到模型参数的实质性变化,包括疾病概念化,数据源,假设和成本.
- 质量评估强调了有关方法的不确定性,异质性,内部一致性以及疾病/干预特征的纳入方面的担忧.
结论:
- 目前对PTSD治疗的基于模型的经济评估显示出相当大的差异.
- 需要产生证据,以促进未来对PTSD干预措施的经济评估的一致性.
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