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Updated: Jan 11, 2026

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
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Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

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元素在引起BRCA1结构变异和乳腺癌易感性方面的作用

Minjae Yu1,2,3, Dahee Jo4, Wonseok Shin5

  • 1Department of Bioconvergence Engineering, Dankook University, Yongin, 16890, Republic of Korea.

Genes & genomics
|November 17, 2025
PubMed
概括

在BRCA1基因中的元素会导致大规模的重组,影响DNA修复和增加癌症风险. 先进的测序和机器学习提高了遗传性乳腺癌的检测和个性化治疗策略.

关键词:
元素中的元素.这就是BRCA1的原因.基因组不稳定性 基因组不稳定性遗传性乳腺癌是一种遗传性乳腺癌.非基同源重组 (NAHR) 是一种非基同源重组.

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