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在儿童中A型肝炎的非典型呈现
Irum Aslam1, Sundus Irshad1, Muhammad Abu Talib1
1Department of Paediatric Gastroenterology, Hepatology and Nutrition, The Children's Hospital and the Institute of Child Health, Multan, Pakistan.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|November 17, 2025
概括
甲型肝炎病毒 (HAV) 感染的非典型表现在儿童中很常见,常见的是炎和多溢液. 年轻的年龄与这些不寻常的症状有很大关系.
科学领域:
- 儿科胃肠病学和肝病学
- 传染性疾病 传染性疾病
- 临床儿科 临床儿科
背景情况:
- 甲型肝炎病毒 (HAV) 感染通常伴有黄,但儿童也可能出现不典型的表现.
- 了解这些非典型表现对于及时诊断和管理至关重要.
- 关键词: 炎, 胆固醇病, 甲型肝炎 病毒, 流, 血小板减少.
研究的目的:
- 为了确定小儿病患者甲型肝炎病毒 (HAV) 感染的非典型表现的频率.
- 为了确定患有HAV感染的儿童常见的非典型表现和相关因素.
主要方法:
- 进行了一项横截面研究,涉及1至18岁的儿童,他们被诊断患有HAV感染.
- HAV感染的诊断是基于临床和实验室发现,记录了非典型的表现.
- 统计分析包括千平方和t测试/曼-惠特尼U测试 (p <0.05显著性).
主要成果:
- 在246名儿童中,60名儿童 (24.4%) 观察到HAV感染的非典型表现.
- 最常见的非典型症状包括炎 (35.0%),多叶膜溢出 (26.7%),血小板缺血 (21.7%),和胆固醇 (15.0%).
- 年龄较小 (p = 0.014),血清胆红素较低 (p < 0.001),INR较高 (p < 0.001) 和血红蛋白较低 (p = 0.004) 与非典型的HAV相关.
结论:
- 在儿童中,HAV的非典型表现很常见,其中最常见的是炎,多发性溢血,血小板缺血和胆固醇症.
- 年轻的年龄与非典型的HAV表现有显著的关联.
- 独特的实验室参数区分了非典型与典型HAV表现的儿童.
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