太空飞行中的骨健康:不完全的骨矿物密度康复1年后,没有增加骨折风险
Benjamin Fiedler1, Todd Phillips, Jad J Lawand
1From the Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX (Dr. Fiedler, Dr. Ghali, and Dr. Adil); the Levy Shoulder to Hand Center at the Paley Orthopaedic Institute, FL (Dr. Phillips); the Department of Orthopaedic Surgery and Rehabilitation, University of Texas Medical Branch, Galveston, TX (Dr. Lawand); the Baylor College of Medicine, Houston, TX (Mr. Noorbakhsh and Mr. Hauck); and the Baylor College of Medicine Center for Space Medicine, Houston, TX (Dr. Adil).
概括
宇航员在太空飞行期间经历了显著的骨矿物质密度 (BMD) 损失,更长的任务导致不完全恢复. 大多数宇航员在任务后的一年内无法恢复BMD到飞行前的水平.
科学领域:
- 整形医疗健康 整形医疗健康
- 太空医学 太空医学
- 骨生理学 骨生理学
背景情况:
- 骨科健康对于宇航员福祉和任务成功至关重要.
- 太空飞行显著影响骨矿物质密度 (BMD).
研究的目的:
- 为了评估空间飞行后各种解剖区域的BMD恢复率.
- 确定任务持续时间和宇航员年龄对BMD恢复和骨折风险的影响.
主要方法:
- 使用美国宇航局宇航员健康数据库进行回顾性队列研究.
- 对94名宇航员的双能放射吸收度和骨折风险数据的分析.
- 关于任务持续时间和宇航员年龄影响的部分分析.
主要成果:
- 部和脊椎的BMD损失在飞行后1年内持续存在.
- 较长的太空飞行 (> 6 个月) 导致脊柱,部和股骨的骨损伤恢复速度较慢和不完全.
- 根据任务持续时间或年龄,在10年骨质疏松性关节骨折风险中没有发现显著差异.
结论:
- 延长太空飞行持续时间与更大的BMD损失和更慢的恢复有关.
- 只有34%和47%的宇航员在飞行后1年内恢复了部和脊椎的飞行前的BMD水平.
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