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Updated: Jan 11, 2026

A High-content Assay for Monitoring AMPA Receptor Trafficking
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与AMPA受体的动态细胞外相互作用

Hana Goldschmidt Merrion1, Casey N Barber1, Santosh Renuse2

  • 1Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Proceedings of the National Academy of Sciences of the United States of America
|November 17, 2025
PubMed
概括

研究人员确定了在突触可塑性期间与AMPA受体 (AMPARs) 相互作用的细胞外蛋白质. 这些相互作用,特别是与NTM等IgLON蛋白的相互作用,影响AMPAR表面的移动性,影响学习和记忆.

关键词:
在AMPA受体上,AMPA受体是伊格隆 (Iglon) 是一个细胞外的细胞外细胞.亲近性蛋白质组学突触性可塑性 突触性可塑性

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