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Updated: Jan 11, 2026

Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
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Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports

Published on: November 28, 2019

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由BMP2/4-ACVR1信号介导的前瘤巨细胞极化在瘤发作过程中调节一个免疫抑制的微环境

Mingchao Wang1, Zhihong Song1, Hao Yuan1

  • 1Tsinghua University, Beijing, China.

Cancer research
|November 17, 2025
PubMed
概括

这项研究揭示了亲瘤巨细胞如何在肺癌中创造"冷"瘤微环境 (cTME). 准ACVR1将cTME转化为"热"的,抑制瘤生长并提供新的治疗策略.

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