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Updated: Jun 20, 2026

Isolation and Analysis of Brain-sequestered Leukocytes from Plasmodium berghei ANKA-infected Mice
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在C6缺乏的小鼠中缺乏补体终端通路活性,在严重疟疾感染的小鼠模型中延长了生存时间

Tomoaki Kamiya1, Yuki Miyasaka2, Hangsoo Kim3

  • 1Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan.

Immunobiology
|November 17, 2025
PubMed
概括

补体终端通路恶化疟疾引起的器官损伤和低血小板数量,导致快速死亡. 抑制这种途径可能有助于治疗严重的疟疾并预防器官衰竭.

关键词:
补充系统的补充系统.感染 感染 感染疟疾:疟疾是一种疾病.多个器官衰竭多个器官衰竭.终端通道 终端通道

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Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...