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Updated: Jan 11, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
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肝炎C病毒NS5A抑制YAP1-HSC70相互作用,从而防止YAP1通过Chaperone介导的自降解

Maria Alethea Septianastiti1,2, Chieko Matsui1, Zihan Xu1

  • 1Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.

The Kobe journal of medical sciences
|November 17, 2025
PubMed
概括

肝炎C病毒 (HCV) 感染通过阻止YAP1蛋白质的降解来破坏伴侣介导自 (CMA). 这导致YAP1的积累和核转移,可能导致HCV的发病.

关键词:
陪伴者介导的自细胞.在HCV病毒感染的过程中,在HSC70中,HSC70是在NS5A中,它是NS5A.一个YAP1一个YAP1

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