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Updated: Jan 11, 2026

Isolation of Murine Lymph Node Stromal Cells
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纤维细胞FLT3L支持淋巴结树突细胞在毛囊间的利基

Sunny Z Wu1, Ryan S Lane1, Christopher Davidson1

  • 1Ophthalmology and Immunology, Genentech, South San Francisco, CA, USA.

Nature immunology
|November 17, 2025
PubMed
概括

淋巴结中的Gremlin1-表达性纤维质网状细胞 (FRC) 提供Fms类的氨酸激酶3连接体 (FLT3L),对树突细胞 (DC) 稳定和功能至关重要. 这一发现澄清了支持DC发育和免疫反应的利基.

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