一个多中心随机单盲临床试验,用于研究慢性心力衰竭患者个性化家庭认知培训计划的影响:SYNAPSE协议
Caroll-Ann Blanchette1,2, Florent Besnier3,4, Emma Gabrielle Dupuy3,4
1Research Centre and EPIC Centre, Montreal Heart Institute, Montreal, QC, Canada. caroll-ann.blanchette-bisson@umontreal.ca.
Trials
|November 18, 2025
概括
这项研究调查了慢性心力衰竭患者的个性化认知训练. 目标是改善这一群体的认知功能和执行功能.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 认知科学 认知科学
背景情况:
- 慢性心力衰竭 (CHF) 患者经常经历认知缺陷,使他们的护理复杂化.
- 目前针对CHF认知缺陷的干预措施往往无法获得或不足.
- 需要可访问的策略来支持心力衰竭患者的认知功能.
研究的目的:
- 评估个性化家庭认知培训计划对患有心血管衰竭的成年人认知功能的影响.
- 探索认知训练的有效性,作为管理心力衰竭认知缺陷的补充策略.
主要方法:
- SYNAPSE试验是一个多中心,单盲,交叉对照试验.
- 54名50岁以上患有慢性心力衰竭的参与者被随机分类.
- 该干预涉及6周的家庭认知训练 (每周1.5小时),以及标准护理,并有评估期.
主要成果:
- 该研究旨在评估对执行功能的影响,作为主要结果.
- 二次结果包括全球认知和神经心理学复合z-scores.
- 结果将表明认知训练在这个患者群体中的有效性.
结论:
- 这项试验将提供关键证据,证明个性化认知训练对心血管疾病患者的认知功能有益.
- 这些发现将指导心力衰竭人口中认知缺陷的管理.
- 这项研究有助于理解慢性疾病中认知健康的可访问干预措施.
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