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Updated: Jan 11, 2026

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
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替代分离SORBS1 影响神经肌肉结合的完整性在肌性发育不良1型

Caroline Hermitte1, Hortense de Calbiac2, Gilles Moulay3

  • 1INSERM/UEPS UMR 861, Paris Saclay University, I-STEM, Corbeil-Essonnes, France.

Journal of cachexia, sarcopenia and muscle
|November 18, 2025
PubMed
概括

肌肉性缩症1型 (DM1) 导致SORBS1外因子25的错误调节,影响神经肌肉结节. 这项研究揭示了SORBS1替代拼接对于肌肉发育和NMJ维护在DM1中至关重要.

关键词:
替代性拼接是一种替代性的拼接.肌性缩症 1 型 1 型神经肌肉结节是一个神经肌肉结节.

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