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Updated: Jan 11, 2026

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在严重抑郁症中解码核编码的线粒体基因:一个多omics视角.

Jing Liao1, Xianyan Wang2, Gaokun Dai3

  • 1Department of Child and Adolescent Psychology, Nanchong Psychosomatic Hospital, Nanchong, Sichuan, China.

Psychological medicine
|November 18, 2025
PubMed
概括

这项研究揭示了关键的线粒体基因,TDRKH和METAP1D,通过多omics分析与主要抑郁症 (MDD) 风险有因果关系. 这些发现为MDD提供了新的治疗点.

关键词:
在GWAS中,GWAS就是GWAS.大型抑郁症主要是抑郁症.线粒体基因是线粒体的基因.基于摘要的门德尔随机化.

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