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关于在非临床毒性研究中使用虚拟控制组的STP市政厅讨论

Kirstin Barnhart1, Brad Bolon2, Laura Boone3

  • 1MBrace Therapeutics, San Diego, California, USA.

Toxicologic pathology
|November 18, 2025
PubMed
概括

在非临床毒性测试中,虚拟控制组 (VCG) 具有减少动物使用的潜力,但需要仔细考虑毒理病理. 同时控制组 (CCG) 对于生成可靠的VCG历史控制数据至关重要.

关键词:
同时的对照组是同步的对照组.历史控制数据 历史控制数据混合控制组是一个混合控制组.非临床毒性测试是指非临床毒性测试.安全评估安全评估的安全评估.合成对照组是一个合成对照组.虚拟控制组是一个虚拟的控制组.

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