相关实验视频

Updated: Jan 11, 2026

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
07:30

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

Published on: May 10, 2018

9.7K

标准化动态葡萄糖测试揭示了人类小岛功能中的供体依赖异质性.

Priyadarshini Gnanasekar1, Chiara Saponaro1, Markus Mühlemann1

  • 1Inserm U1190, CHU Lille, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Univ. Lille, Lille, France.

Cell transplantation
|November 18, 2025
PubMed
概括

与静态方法相比,动态外周更好地揭示了人类小岛的葡萄糖刺激胰岛素分泌 (GSIS) 异质性. 捐赠者的BMI和HbA1c显著影响胰岛素分泌模式,突出了贝塔细胞功能变异性的关键因素.

关键词:
美国GSIS是GSIS.胰岛素分泌的胰岛素分泌.岛屿移植移植小岛移植边缘化 边缘化 边缘化

更多相关视频

Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol08:04

Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol

Published on: November 3, 2023

2.4K
Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms08:16

Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms

Published on: March 15, 2024

2.1K

相关概念视频

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion01:27

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
Insulin and C-peptide are...
2.1K