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Updated: Jan 11, 2026

Identification of Footprints of RNA:Protein Complexes via RNA Immunoprecipitation in Tandem Followed by Sequencing RIPiT-Seq
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Published on: July 10, 2019

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基于结构的RiPP识别元素的发现和定义

Miriam H Bregman1, Dillon P Cogan2, Kyle E Shelton1

  • 1Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

mSystems
|November 18, 2025
PubMed
概括

这项研究通过将基于结构的搜索与AlphaFold预测相结合来增强RiPP发现,识别了9万多个RiPP识别元素 (RRE) 和13个识别动机. 这提高了基因组挖掘的准确性,并扩大了对隐藏的RiPP生物合成途径的访问.

关键词:
这就是RiPPs.基因组采矿是如何进行的分子识别分子识别自然产品是自然产品的产品.蛋白质:相互作用核糖体酸是一种体.

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