在右心室,无,深和左捆分支区域节律器之后,膜和心室功能的比较
Anja Zhou1,2, Isabelle Andersson1,2, Mutaz Alkalbani2
1Department of Clinical Physiology, Karolinska University Hospital, and Karolinska Institute, Stockholm, Sweden.
Pacing and clinical electrophysiology : PACE
|November 18, 2025
概括
左捆支部区域 (LBBA) 节拍器植入显示了与右心室顶部 (RVA),深隔膜 (DS) 和无节拍相比,三回 (TR), mitra回 (MR) 和左心室喷射分数 (LVEF) 的更有利变化.
科学领域:
- 心脏病学 心脏病学
- 心脏电生理学 心脏电生理学
- 心血管成像 - 心血管成像
背景情况:
- 心脏起器植入可以影响心脏功能,特别是膜反和心室性能.
- 右心室角 (RVA) 节奏与三回 (TR),心室回 (MR) 和左心室喷射分数 (LVEF) 的变化有关.
- 有限的数据表明,像左捆分支区域 (LBBA),深隔膜 (DS) 或无步行等替代步行场所是否能减轻这些风险.
研究的目的:
- 为了比较TR,MR和LVEF在心脏起器植入后在不同领先位置的变化.
- 评估RVA,LBBA,DS和无心脏起器植入物对膜功能和心室性能的影响.
主要方法:
- 对386名患者进行了回顾性分析,这些患者因鼻节功能障碍或心房塞而接受了新的心脏起器植入.
- 植入前和植入后心声学被用来评估TR,MR和LVEF的变化.
- 统计分析包括克鲁斯卡尔-瓦利斯,奇平方测试和多变量顺序逻辑回归.
主要成果:
- 在TR等级的变化显著不同于心脏起器类型 (p=0.01),与LBBA节奏显示没有恶化.
- 无 (OR 2.41) 和DS (OR 2.44) 心脏起器预测TR恶化与LBBA节奏相比.
- 在心脏起器类型之间的MR等级 (p=0.03) 和LVEF (p<0.01) 的变化中观察到显著差异.
结论:
- 心脏起器植入部位会影响TR,MR和LVEF的变化.
- 与RVA,无和DS节奏相比,LBBA心脏起器植入与膜和心室功能方面更有利的结果有关.
相关概念视频
Anatomy of the Heart
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
Location and Orientation of the Heart
The human heart, despite its modest size and weight, is an organ of remarkable strength and endurance. Roughly the size of a fist, the heart weighs between 250 and 350 grams and is nestled within the mediastinum, the medial cavity of the thorax. It extends obliquely for about 12 to 14 cm, resting on the superior surface of the diaphragm. The heart is positioned anterior to the vertebral column and posterior to the sternum, with two-thirds of its mass lying to the left of the midsternal line.
Chambers of the Heart
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
Heart Valves
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
Anatomy of the Heart
The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...


