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Updated: Jan 6, 2026

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EVOLVE平台,一个具有集成CD2共刺激的三种特异性T细胞参与剂,用于固体和血液瘤的治疗

Oksana A Sergeeva1, Guixian Jin1, Mohosin Sarkar1

  • 1EvolveImmune Therapeutics, Inc., Branford, CT 06405.

Proceedings of the National Academy of Sciences of the United States of America
|November 18, 2025
PubMed
概括

将CD2代刺激集成到T细胞参与剂 (TCE) 中,可以提高T细胞活力和效应器功能. 这种新的EVOLVE平台改善了癌症免疫治疗的瘤杀伤和响应耐久性.

关键词:
一个T细胞参与者.整体刺激的代谢刺激免疫瘤学 免疫瘤学免疫疗法 免疫疗法

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