感知日常歧视及其通过不同人群中抑郁症对认知功能的影响:HABS-HD研究
Edna Patricia Mendoza1, Emma Nolan2,3, Nicole Phillips4,5
1Department of Population and Community Health, University of North Texas Health Science Center, Fort Worth, TX, USA.
Journal of Alzheimer's disease : JAD
|November 18, 2025
概括
感知到的歧视会影响认知功能,抑郁症对西班牙裔和非西班牙裔白人起到调解作用. 在非西班牙裔黑人中没有观察到这种途径,突出显示了潜在的认知健康差异.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 以前的研究将感知到的歧视与认知障碍联系起来.
- 抑郁症被认为是这种关系中的潜在调解者.
- 了解这些跨不同种族和种族群体的联系对于健康公平至关重要.
研究的目的:
- 检查和比较感知日常歧视和认知功能之间的关系.
- 调查抑郁症在这些关联中的调解作用.
- 根据种族/种族分层分析:非西班牙裔黑人 (NHB),西班牙裔和非西班牙裔白人 (NHW).
主要方法:
- 使用结构方程建模 (SEM) 来分析数据.
- 包括来自健康和衰老大脑研究 - 健康差异队列的1267名参与者.
- 按种族/种族分层分析 (NHB: 685,西班牙裔: 302,NHW: 280).
主要成果:
- 抑郁症完全调解了西班牙裔和NHW的感知歧视和认知功能之间的关联.
- 在所有群体中,感知到的歧视和抑郁症之间发现了积极的联系.
- 在除NHB外的所有组中观察到抑郁症和认知功能之间的负相关性.
结论:
- 抑郁症调解了西班牙裔和NHW的歧视-认知联系,但不是NHB.
- 研究结果表明,NHB中影响认知健康的独特途径.
- 强调需要对少数群体中阿尔茨海默病和认知健康差异进行研究.
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