宁米泰囊促进了尿道镜霍尔激光光疗术后的残留碎片清除:一个多中心随机对照试验
Urologia internationalis
|November 18, 2025
概括
宁米泰囊 (NMT) 帮助在激光石术后清除剩余的石块碎片. 将NMT与tamsulosin结合起来,可显著改善无结石率,并缩短排泄时间,提供有益的治疗选择.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學.
- 药理学 药理学是指药理学的学科.
背景情况:
- 尿路透镜Holmium激光石 (Ho:YAG-URS) 对结石有效,但可以留下残留碎片.
- 促进这些残留碎片的清除对于患者的治疗结果至关重要.
- 传统中医 (TCM) 提供了后lithotripsy护理的潜在治疗途径.
研究的目的:
- 评估Ningmitai囊 (NMT) 在Ho:YAG-URS后清除残留尿管碎片的疗效.
- 评估NMT和tamsulosin对残留石块驱逐的联合作用.
- 将治疗结果与没有药物治疗的对照组进行比较.
主要方法:
- 一个多中心,前性,随机对照试验,涉及222名患有远端尿管残留碎片的患者.
- 患者随机分为三个组:对照组,单独使用NMT,或将NMT与tamsulosin结合使用.
- 主要结局是4周后的无结石率 (SFR),次要结局包括驱逐率和时间.
主要成果:
- 组合组的SFR (98.91%) 与单独使用NMT (92.21%) 和对照组 (76.19%) 相比显著更高.
- 与对照组相比,单独的NMT也显著改善了SFR (p = 0.023).
- 与对照组相比,组合疗法显著减少了无石头时间和排泄时间 (p < 0.0001).
结论:
- 宁米泰囊 (NMT) 有效地加速了Ho:YAG-URS.之后的残留碎片的驱逐.
- 当NMT与tamsulosin结合使用时,观察到一个协同效应,增强了清除.
- 单独使用NMT或与tamsulosin结合使用,具有有益的治疗策略,特别是对于小残留碎片.
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