Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

419
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
419
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

454
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
454
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

468
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
468
Importance of Need for Affiliation01:25

Importance of Need for Affiliation

250
The need for affiliation is a fundamental human motive that drives individuals to form and maintain interpersonal relationships. This universal drive varies in intensity among individuals due to genetic predispositions and life experiences, shaping it into a relatively stable personality trait. Social inclusion enhances emotional well-being by fulfilling the need for affiliation, whereas social exclusion leads to distress, negative emotions, and cognitive impairments.Psychological and Emotional...
250
Introduction to Psychological Disorders01:19

Introduction to Psychological Disorders

1.1K
Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
1.1K
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

589
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
589

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Individual differences in speech monitoring: Functional and structural correlates of delayed auditory feedback.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Evolution of the frontal aslant tract and implications for primate vocalization and human speech.

Nature communications·2026
Same author

Adverse childhood experiences and risk of non-mental medical diseases in adulthood: an umbrella review.

EClinicalMedicine·2026
Same author

Brain Morphology Mediators of the Association of Childhood Trauma With Bipolar Disorder: An International ENIGMA Bipolar Disorder Working Group Study.

JAMA psychiatry·2026
Same author

Evaluating the methodological quality of coordinate-based meta-analyses: the qual-CBMA checklist.

Frontiers in neuroimaging·2026
Same author

Atypical cytokine profiles in people on the autism spectrum: a comprehensive systematic review and meta-analysis including 54 cytokines.

Molecular psychiatry·2026

相关实验视频

Updated: Jan 11, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

11.1K

自杀思想和行为中的结构连接异常:一个元分析.

Lena Lim1,2, Joaquim Radua3,4, Ahmad Beyh5

  • 1Institute for Human Development and Potential, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. lena.lim@kcl.ac.uk.

Translational psychiatry
|November 18, 2025
PubMed
概括

自杀的想法和行为 (STBs) 与白质异常有关. 这次元分析发现,关键的大脑路径中的分数异性变异性 (FA) 减少,这表明STB患者的情绪和感官处理受损.

更多相关视频

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

879
Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

15.7K

相关实验视频

Last Updated: Jan 11, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

11.1K
Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

879
Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

15.7K

科学领域:

  • 神经科学是一个神经科学.
  • 精神病学是一个精神病学.
  • 医疗成像医学成像

背景情况:

  • 自杀的想法和行为 (STBs) 是一个重要的公共卫生问题.
  • 研究主要集中在灰质异常,对性传播疾病中白质区域的关注较少.

研究的目的:

  • 对扩散张力成像 (DTI) 研究进行第一个元分析,以确定与对照人群相比,在性病患者中发现强大的白质微观结构异常.
  • 为了阐明在STB中受损的特定白质路径.

主要方法:

  • 一个基于voxel的14个DTI数据集的元分析,包括289个有STB的个人和506个对照.
  • 利用异性质效应大小签名差异映射来分析分数异性质 (FA) 差异.

主要成果:

  • 与对照人群相比,患有STB的个体在双边下侧纵向囊,下额头囊囊,未切割囊,,环膜束和体体中表现出明显较低的FA.
  • 没有任何地区显示FA的增加. 在成年人和无毒药物小组中,研究结果一致.
  • 在右侧前边缘尾集群中降低的FA在年轻人和患有性病的女性中更为明显.

结论:

  • 性病与微观结构性白质异常有关,特别是在腹部前边缘,视觉边缘-OFC和体路径.
  • 这些发现表明,STB患者的情绪和感官处理中涉及的神经通路受损.
  • 了解这些神经生物学异常对于开发有针对性的治疗方法来减少自杀死亡至关重要.