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Updated: Jan 11, 2026

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DNA复制叉速度作为皮层神经发生的节奏器

Jianhong Wang1,2,3, Yifan Kong1,2,3, Xuezhuang Li1,4

  • 1State Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, P.R. China.

Nature communications
|November 18, 2025
PubMed
概括

复制叉速度影响大脑发育. 在神经前代细胞中删除MCMBP会加快这种速度,导致DNA损伤,小头症和小鼠的焦虑行为.

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