患有或没有视力障碍的青光眼患者的死亡率和自杀风险:全国范围的队列研究
Kyoung Ohn1, Kyungdo Han2, Younhea Jung3
1Department of Ophthalmology, College of Medicine, Yeouido St. Mary's Eye Hospital, The Catholic University of Korea, 10, 63-ro, Yeongdeungpo-gu, Seoul, 07345, Republic of Korea.
Scientific reports
|November 18, 2025
概括
青光眼患者,尤其是视力受损患者,面临死亡率增加的风险,包括自杀. 视力障碍显著提高了年轻人和女性的死亡率,而青光眼患者的自杀风险在所有年龄段和性别上升.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 玻璃眼是导致不可逆转失明的主要原因.
- 绿眼病对死亡率和自杀风险的影响,包括视力受损和没有视力受损,仍然不完全理解.
研究的目的:
- 调查青光眼,视力障碍和全因和因特定死亡率,包括自杀风险之间的关联.
- 分析年龄和性别对这些死亡风险的影响.
主要方法:
- 使用韩国国家医疗保险服务数据 (2009-2020) 进行的回顾性队列研究.
- 包括4,056,650名年龄≥20岁的个体,分为健康对照组,视力不减弱的青光眼和视力减弱的青光眼.
- 使用原始和调整模型计算的危险比率 (HR),以年龄和性别分层.
主要成果:
- 青光眼患者,特别是视力受损患者,全因死亡率显著上升 (调整HR [aHR] 1.346).
- 视力受损的玻璃眼患者因特定原因增加的死亡率包括代谢,循环,呼吸系统疾病和自杀.
- 自杀死亡率风险在两组青光眼中都逐渐增加,视力障碍组的aHR (2.486) 是最高的.
- 视力受损的眼光与视力受损不成比例地增加了年轻人和女性的死亡率.
- 自杀死亡风险在所有年龄和性别的视力受损的格劳科马患者中都较高.
结论:
- 玻璃眼,特别是与同时存在的视力障碍相关,与整体死亡率的增加有关.
- 眼患者的视力障碍增加了各种疾病和自杀的风险.
- 针对性干预和支持对青光眼患者至关重要,特别是年轻女性,以减轻死亡风险.
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