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Updated: Jan 11, 2026

Pan-myeloid Differentiation of Human Cord Blood Derived CD34+ Hematopoietic Stem and Progenitor Cells
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MAFB调节了造血干细胞的增殖和维持

Saki Asano1, Ching-Wei Liao1,2, Yurina Matsunaga1

  • 1Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

Scientific reports
|November 18, 2025
PubMed
概括

MAFB在胎儿和成人造血干细胞 (HSC) 中发挥着不同的作用. 删除MAFB可以促进胎儿的HSC增殖,但会损害成人HSC的维持,从而影响长期的再生.

关键词:
细胞周期调节细胞周期调节造血干细胞 (HSCs) 是一种细胞.在MAFBB中,MAFBB是MAFB,MAFB是MAFB.自我更新是一种自我更新.干细胞耗尽导致的干细胞耗尽.

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