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Updated: Jan 11, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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具有潜在的多目标抑制性质的抗质4-piperidone-1-phosphonothioates具有潜在的多目标抑制性质

Mohamed S Bekheit1, Siva S Panda2, Benson M Kariuki3

  • 1Department of Pesticide Chemistry, National Research Centre, Dokki, 12622, Giza, Egypt.

Scientific reports
|November 18, 2025
PubMed
概括

新的酸化合物显示出强大的抗癌活性,在抗乳腺癌,结肠癌和皮肤癌细胞系方面表现优于现有的药物. 这些药物还抑制了与癌症相关的关键蛋白质,如MDM2和拓酶,这表明它们有可能成为多向癌症疗法.

关键词:
4 - 皮皮里-1 - 斯诺酸癌症 癌症 癌症 癌症在MDM2-p53中使用.分子建模分子建模拓糖酶是一种多糖酶.

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