"区块上的新孩子"-MDDM作为狂喜药片中的新成分
Bogumiła Byrska1, Karolina Masier1, Roman Stanaszek1
1Institute of Forensic Research, Krakow, Poland.
Journal of forensic sciences
|November 19, 2025
概括
在波兰查获的狂喜药片含有3,4-甲基二氧化甲胺 (MDMA),MDA,以及一种新物质3,4-甲基二氧化-N,N-二甲胺 (MDDM). 精神活性药物的不可预测混合物对公共健康构成重大风险.
科学领域:
- 法医化学 法医化学
- 分析化学 分析化学
- 药理学 药理学是指药理学的学科.
背景情况:
- 狂喜药片通常含有未公开的精神活性物质,除了3,4-甲基二氧化甲胺 (MDMA).
- 新型精神活性物质 (NPS) 存在重大风险,因为其成分和作用尚不清楚.
- 非法毒品市场充满活力,合成路线和产品成分不断变化.
研究的目的:
- 为了分析波兰扣押的"突击队员"形状的狂喜药片的化学成分.
- 识别和量化现有的活性精神活性物质,包括新型化合物.
- 评估检测到的药物混合物的潜在公共卫生影响.
主要方法:
- 气色谱-质谱 (GC-MS) 用于物质的识别.
- 使用光二极管阵列检测 (UHPLC-PDA) 的超高性能液态色谱进行量化.
- 分析了2020年至2021年间被查获的150片狂喜药片.
主要成果:
- 检测到了MDMA,3,4-甲基二氧化胺 (MDA) 和3,4-甲基二氧化-N,N-二甲基胺 (MDDM).
- MDDM是一种新型的乙烯胺衍生物,首次在波兰的发作中被发现.
- 其中MDA的度最高 (26-74毫克),其次是MDDM (11-28毫克) 和MDMA (3-11毫克).
结论:
- 这项研究强调了街头狂喜的复杂和可变的化学成分.
- 多种精神活性物质的同时出现,包括MDDM,可能会导致不可预测的协同效应和增加毒性.
- 持续的法医监测和公众意识对于解决与合成药物市场相关的风险至关重要.
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