杆菌感染与医院获得的上部胃肠道出血之间的关联:一项前性病例控制研究
Setthachai Piwchan1, Ekawee Sripariwuth2, Suppana Chuensakul2
1Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand. setthachaipw@gmail.com.
杆菌 (H. pylori) 感染与住院上部胃肠道出血 (UGIB) 的更高风险有关. 在患有UGIB的住院患者中,早期的H. pylori测试可以改善患者的护理.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 医院 医院 医疗 医疗 医疗 医疗
背景情况:
- 医院内出血是一个重大问题,增加了住院和死亡率.
- 长时间的机械通风和凝血病是出血的确立危险因素.
- 杆菌 (H. pylori) 在医院获得的上部胃肠道出血 (UGIB) 中的作用需要进一步调查.
研究的目的:
- 评估当前的H. pylori感染与住院患者的UGIB发生之间的关联.
- 确定导致医院内UGIB的风险因素.
主要方法:
- 进行了一项年龄和性别匹配的病例控制研究,采用前性数据收集.
- 目前的H. pylori感染是通过快速测试来诊断的.
- 用多变量条件逻辑回归分析来确定关联.
主要成果:
- 在研究人群中,H. pylori感染的患病率为32% (87例UGIB病例,333例对照).
- 杆菌感染与增加住院UGIB的几率有显著的关联 (调整后OR: 1.97).
- 长时间的机械通风也与UGIB显著相关 (调整后OR:2.23).
结论:
- 甲状腺杆菌感染是医院内UGIB的独立风险因素,类似于长期机械通风.
- 建议在患有UGIB的住院患者进行向的H. pylori测试,以指导适当的管理.
- 早期识别和治疗H. pylori可能有助于减少医院获得的UGIB的发生率和严重程度.
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