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在摩洛哥的乙型肝炎表面抗原血清流行 (2000-2024):系统性审查和元分析

Mourad Feindiri¹, Hakima Kabbaj², Mouna Salihoun³

¹Central Laboratory of Virology, Faculty of Medicine and Pharmacy of Rabat, Ibn Sina University Hospital Center, Mohammed V University, Rabat, Morocco. mouradfeindiri@gmail.com.

BMC infectious diseases

|November 19, 2025

概括

摩洛哥的乙型肝炎病毒 (HBV) 感染率很低,HBsAg总率为1.33%. 这表明国家控制措施取得了进展,尽管高风险群体需要持续关注.

科学领域:

流行病学流行病学
公共卫生公共卫生
传染性疾病传染性疾病

背景情况:

乙型肝炎病毒 (HBV) 感染是一个重大的全球健康问题,影响着全球数百万人.
慢性HBV感染导致严重的健康后果,包括肝病和死亡率.
摩洛哥缺乏关于乙型肝炎负担的全面流行病学数据.

研究的目的:

系统地审查和对过去25年来摩洛哥乙型肝炎患病率的研究进行元分析.
填补关于摩洛哥HBV负担的综合流行病学数据的空白.
评估摩洛哥不同地区和亚种群的HBV流行程度.

主要方法:

在主要数据库 (PubMed,Scopus,Web of Science,Google Scholar) 中进行了全面的文献搜索.
包括2000年至2024年间发表的观察性研究,报告了摩洛哥的HBsAg患病率.
使用DerSimonian-Laird随机效应模型来计算聚合流行率.

主要成果:

分析了包括34个队列和750,784个人的30项研究.
摩洛哥的HBsAg综合流行率为1.33% (95% CI:1.07-1.61).
患病率差异很大,在军人群体中患病率最低 (0.36%),在高危人群中患病率最高 (5.43%).

结论:

摩洛哥正在向HBV的低流行率过渡,这可能是由于国家控制措施和疫苗接种计划.
需要持续努力才能保持进展,并应对HBV管理的挑战,特别是在弱势群体中.
这些发现突出了HBV负担中特定亚群的差异,需要有针对性的干预措施.

关键词:

这就是HBsAg.乙型肝炎 B 型肝炎摩洛哥摩洛哥摩洛哥摩洛哥摩洛哥摩洛哥流行程度流行程度血清的流行程度是如此.

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