在整个招募过程中,患者的社会人口统计特征被随机对照的行为试验
Deborah Rohm Young1, Melissa Preciado2, Viviann Soto2
1Department of Research & Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, Pasadena, CA, 91101, USA. Deborah.r.young@kp.org.
Trials
|November 19, 2025
概括
使用电子健康记录 (EHR) 进行体育活动试验的招聘发现,糖尿病患者,男性,西班牙裔和西班牙语人士的入学可能性较低. 邻里贫困没有影响参与率.
科学领域:
- 临床试验 临床试验
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 有效的参与者招募对于临床试验的成功至关重要.
- 这项研究评估了使用电子健康记录 (EHR) 和电话随访的招聘策略,用于体力活动干预试验.
- 该试验名为NCT0445168,于2020年6月24日注册.
研究的目的:
- 评估基于EHR的招聘在体育活动干预试验中识别和招募参与者的有效性.
- 确定影响参与糖尿病前期或糖尿病患者体育活动试验的社会人口统计学因素.
主要方法:
- 一组11152名患有糖尿病前期或糖尿病和低体力活动的患者通过EHR被确定.
- 潜在的参与者收到电子邮件或邮寄信件,随后多达5次电话联系尝试.
- 收集了社会人口统计数据,并使用统计测试 (皮尔森的千平方,费舍尔的精确,威尔科克森的等级总和) 来分析招聘阶段.
主要成果:
- 招聘发生于2020年7月至2023年9月,目标为482名参与者.
- 在11152名确诊患者中,有4033人通过电话联系. 接触者更有可能患有糖尿病前期,女性,不太可能是西班牙裔或更喜欢西班牙语.
- 在接触的患者中,721人表示同意,显示出更高的糖尿病前期,女性,以及较低的西班牙语语言偏好率. 451名受试者被随机分配.
结论:
- 在EHR驱动的招聘过程中,发现了参与试验的差异.
- 患有糖尿病,男性,西班牙裔族裔和西班牙语偏好的人在体育活动试验中代表性不足.
- 根据邻里贫困指数,没有观察到参与率的显著差异.
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