确定与COVID-19死亡率相关的精神病发病和并发病模式. 来自加泰罗尼亚的基于登记的队列研究
Mireia Felez-Nobrega1,2, Iago Giné-Vázquez1,2, Anna Monistrol-Mula1,2,3
1Group of Epidemiology of Mental Disorders and Ageing, Sant Joan de Déu Research Institute, Esplugues de Llobregat, Barcelona, Spain.
概括
成年人中精神障碍的数量显著增加了COVID-19死亡风险. 这项研究强调了精神病诊断的整体负担,而不是特定的模式,作为COVID-19结果的关键因素.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 精神病学是一个精神病学.
背景情况:
- 关于精神病发病率和COVID-19死亡率之间的联系的证据有限.
- 了解这种关联对于公共卫生战略至关重要.
研究的目的:
- 评估精神疾病数量与COVID-19死亡率之间的关联.
- 为了探索特定的精神病学并发症模式是否影响COVID-19死亡风险.
主要方法:
- 利用来自加泰罗尼亚公共卫生系统的匿名电子健康记录.
- 将患有精神障碍的成年人 (2017-2019) 与匹配的对照人群进行比较.
- 分析了COVID-19死亡风险 (2020年2月至12月),使用赔率比率和K-means集群分析.
主要成果:
- 包括785,378名成年人 (392,689人患有精神障碍).
- 随着精神疾病的数量增加,死亡风险增加 (OR 1.23至5.21).
- 在COVID-19幸存者和死亡者之间确定了可比的精神病理并发症概况.
结论:
- 越来越多的精神病诊断与更高的COVID-19死亡率有关.
- 特定的并发症模式对结果的差异影响有限.
- 多重诊断的整体负担,而不是特定的组合,影响COVID-19死亡率.
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