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Updated: Jun 8, 2026

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SERSμDrop:一个通过SERS成像研究细胞间通信的平台.

Paula Piñeiro1,2,3, Judith Langer1,3, Joaquin Seras-Franzoso4,5

  • 1CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Donostia-San Sebastián, 20014, Spain.

Small (Weinheim an der Bergstrasse, Germany)
|November 19, 2025
PubMed
概括

研究人员开发了一种微流体平台SERSμDrop,以单细胞分辨率通过细胞外囊泡 (EVs) 追踪细胞与细胞之间的通信. 这个工具精确地监测癌细胞和纤维细胞之间的EV转移,推动癌症研究.

关键词:
这是SERS成像.在 SERS 标签中使用 SERS 标签.细胞封装的细胞封装.异位细胞形成的表细胞化.细胞外囊泡中的细胞外囊泡.这些微粒是微滴.

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Cell-surface Signaling01:21

Cell-surface Signaling

Hormones—or any molecule that binds to a receptor, known as a ligand—that are lipid-insoluble (water-soluble) are not able to diffuse across the cell membrane. In order to be able to affect a cell without entering it, these hormones bind to receptors on the cell membrane. When a first messenger, a hormone, binds to a receptor, a signal cascade is set off, causing second messengers, proteins inside the cell, to become activated, resulting in downstream effects.