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Updated: Jan 11, 2026

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训练有素的免疫力通过促进协纤维细胞铁细胞抵抗来加剧炎症性关节炎的进展

Haibo Su1, Baoying Zhang1, Qiudi Deng1

  • 1Department of Critical Care Medicine, GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macao Joint Laboratory for Cell Fate Regulation and Diseases, State Key Laboratory of Respiratory Disease, Guangzhou Key Laboratory of Prevention and Treatment of Multiple Organ Dysfunction Syndrome, the Second Affiliated Hospital, Guangzhou Medical University, Dongfengxi Road 195, Guangzhou, Guangdong, 510260, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 19, 2025
PubMed
概括

训练有素的免疫力,由β-葡萄糖驱动,通过重编程巨细胞,恶化炎症性关节炎. 用iFSP1和雷莫德林准训练免疫力,为关节炎提供了一个新的治疗策略.

关键词:
铁性化 (ferroptosis) 是一种炎症性关节炎是一种炎症性关节炎.天生的免疫记忆天生的免疫记忆训练有素的免疫力训练有素的巨细胞

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