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Updated: Jan 11, 2026

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克服PEG抗原性:统计PEG异构体减少抗体结合

Mareike Deuker1, Dominik Schulz2, Kaloian Koynov1

  • 1Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 19, 2025
PubMed
概括

随机PEG (rPEG) 通过破坏抗体结合来降低免疫反应. 这种新型聚合物可以防止抗PEG抗体,为先进的生物医学应用提供了有前途的替代方案.

关键词:
抗-PEG抗体的抗体.合作聚合的共聚合.聚乙烯糖醇 (PEG) 是一种聚乙烯基醇.随机进行的PEG.环开放聚合的聚合方式

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