加速度计衍生体力活动和发生骨折的风险:基于人口的队列研究
Yan Luo1,2, Yu Jiang1,2,3, Shuhuai Tan1,2,3
1Senior Department of Orthopaedics, Chinese PLA General Hospital, Beijing, China.
International journal of surgery (London, England)
|November 19, 2025
概括
参与中度体力活动 (PA) 显著降低中年成人骨折的风险. 过度的PA不提供额外的好处,甚至可能是有害的.
科学领域:
- 生物医学科学 生物医学科学
- 流行病学 流行病学
- 老年学是一门学科.
背景情况:
- 关于加速度计测量身体活动 (PA) 和骨折风险的数据有限.
- 以前的研究依赖于自我报告的PA,这可能是不准确的.
- 了解客观PA测量和骨折之间的剂量反应关系至关重要.
研究的目的:
- 估计加速器测量PA和中年成年人中发生骨折的风险之间的剂量反应关系.
- 为了研究不同水平的PA和不同类型的骨折之间的关联.
主要方法:
- 基于人口的队列研究,包括81,367名英国生物库参与者.
- 基于加速器的PA数据收集了整整一周的时间.
- 主要暴露:总PA的总加速平均值 (mg); 替代暴露:在中度至剧烈活动中的时间比例.
主要成果:
- 在8.1年的时间里,4.6%的患者出现复合骨折,3.2%的患者患有骨质疏松,0.7%的患者患有部骨折,0.4%的患者患有脊椎骨折.
- 与低PA (≤22.53 mg) 相比,中度PA水平 (22.53-32.56 mg) 与复合骨折风险降低有关.
- 对PA和所有骨折类型观察到的U形曲线,表明非线性关系.
结论:
- 适度的PA水平 (22.5332.56毫克) 显著降低发生骨折的风险.
- 超过32.56毫克的PA水平显示益处减少或可能减弱.
- 建议强调从事中等水平的身体活动,以预防骨折.
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