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含有英多尔的抑制剂具有提高的有效性,向Mycobacterium tuberculosis的旋转酶

Shankar Bhattarai1, Vinay Shankar Tiwari1, Benjamin Tam1

  • 1Department of Chemistry, Ben-Gurion University of the Negev, David Ben-Gurion Blvd. 1, Beer-Sheva 8410501 P.O Box 653, Israel.

NAR molecular medicine
|November 19, 2025
PubMed
概括

研究人员发现了新的小分子抑制剂,针对结核病引起的细菌Mycobacterium tuberculosis中的陀螺酶. 这些以醇为基础的化合物显示出治疗耐药结核病感染的前景.

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