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南非胸腔学会就跨支气管肺冷活检用于间歇性肺病的共识声明

C F N Koegelenberg¹, N Singh¹, A Esmail²

¹Division of Pulmonology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.

African journal of thoracic and critical care medicine

|November 19, 2025

概括

与手术肺活检相比,跨支气管肺冷活检 (TBLC) 为诊断间歇性肺病 (ILD) 提供了更安全,更具成本效益的方法. 这种微创技术提供了足够的组织样本,用于准确的组织病理学分析.

科学领域:

肺部病理学肺部病理学
医学诊断医学诊断医学诊断
干预性放射学干预性放射学

背景情况:

手术肺活检 (SLB) 是诊断需要组织学确认的间歇性肺病 (ILD) 的黄金标准.
通过支气管叉切片活检得出的样本不足以进行确的分析.
跨支气管肺冷活检 (TBLC) 是一种具有更高的诊断产量和更好的组织完整性的最小侵入性替代方案.

研究的目的:

评估跨支气管肺冷活检 (TBLC) 作为间歇性肺病 (ILD) 的诊断工具.
将TBLC与手术肺活检 (SLB) 等传统诊断方法进行比较.
评估TBLC在ILD诊断中的安全性,有效性和成本效益.

主要方法:

在全身麻醉或有意识镇静下,使用或不使用人工气道进行TBLC.
支气管阻塞剂用于控制出血,在光镜指导下获得活检.
采集至少四个充足的组织样本 (>5毫米),并进行特殊的术后护理.

主要成果:

与跨支气管切片活检相比,TBLC提供了更大的块样.
国际社会有条件地建议TBLC作为ILD的潜在一线诊断工具.
TBLC是SLB的成本效益和更安全的替代品,特别是在资源有限的环境中.

结论:

南非胸腔学会倡导TBLC作为ILD的第一线诊断模式,需要组织学.
与SLB相比,TBLC的成本和发病率较低.
加强当地TBLC专业知识对于提高ILD诊断准确性至关重要.

关键词:

低温生物检查 (Cryobiopsy) 是一个非常简单的方法.间歇性肺病间歇性肺病干预性肺病学干预性肺病学

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