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乙肝血清检测和维生素D值:季节性评估

Adem Keskin^1,2, Mehmet Hakan Taskin³, Mukadder Erdem⁴

¹Department of Medicine Biochemistry, Institute of Health Sciences, Aydın Adnan Menderes University, Aydın, Türkiye.

Journal of clinical practice and research

|November 19, 2025

概括

维生素D缺乏可能与乙型肝炎病毒 (HBV) 感染标志物有关. 对于HBV血清测试阳性的人,建议监测维生素D水平.

科学领域:

肝病学肝病学是一种肝病学.
免疫学免疫学免疫学
内分泌学在内分泌学.

背景情况:

乙型肝炎病毒 (HBV) 感染是一个全球性的健康问题,疾病进展受到病毒抗原和自身免疫反应的影响.
维生素D缺乏与各种疾病的严重程度有关,这表明它可能在HBV病变发生过程中发挥作用.

研究的目的:

调查乙型肝炎病毒 (HBV) 血清标志物与25-氧维生素D水平之间的关联.

主要方法:

分析了120,004个HBV血清测试 (HBsAg,HBeAg,抗HBsAg,抗HBeAg,抗HBc IgG,抗HBc IgM) 和62,835个25-氧维生素D测试.

主要成果:

在不同季节的HBsAg阳性个体中,与HBsAg阴性个体相比,观察到较低的25-氧维生素D水平.
对抗HBsAg和抗HBcIgG呈阳性个体的25-氧维生素D水平比他们的负面对手更高.
在对抗HBeAg负的个体中,观察到低于最佳的25-氧维生素D水平.

结论:

在25-基维生素D水平和乙型肝炎病毒血清标记的阳性之间存在潜在的关系.
建议在受HBV影响的人群中监测维生素D状态.

关键词:

抗B型肝炎的表面抗原.乙型肝炎表面抗原B型肝炎表面抗原乙型肝炎病毒的感染.血清学测试测试血清学测试维生素D缺乏症维生素D缺乏症

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