印度没有肥胖的青少年的糖尿病:一个未被认可的表型
Rashi Agrawal1, Akhila Bhandarkar2, Nitin Kapoor3,4
1Department of Endocrinology, Kokilaben Dhirubhai Ambani Hospital, Navi Mumbai, Mumbai 400053, Mahārāshtra, India.
World journal of clinical pediatrics
|November 19, 2025
概括
印度青少年的2型糖尿病 (T2DM) 正在增加,与肥胖有关. 然而,T2DM也会影响正常体重的个体,强调需要评估BMI以外的中心脂肪.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 儿科 儿科 儿科
背景情况:
- 青少年2型糖尿病 (T2DM) 是印度日益关注的问题.
- 肥胖经常被认为是这群人群中T2DM的主要驱动因素.
- 以前的研究表明,超重,肥胖,社会经济因素和教育状况是导致15-19岁印度青少年高血糖的因素.
研究的目的:
- 分析印度青少年T2DM的患病率.
- 为了研究中心脂肪在T2DM超出身体质量指数 (BMI) 测量的作用.
- 为了突出印度青少年"正常体重肥胖"的问题.
主要方法:
- 对印度青少年T2DM和肥胖现有研究的审查和分析.
- 专注于正常BMI和低于正常BMI受试者的高血糖数据.
- 强调中央脂肪度指标的重要性.
主要成果:
- 印度青少年中T2DM很普遍,即使BMI正常或低于正常.
- 很大一部分印度青少年表现出"正常体重肥胖",这可能会被忽视.
- 常规的BMI测量可能无法充分捕捉所有青少年高血糖的风险.
结论:
- 中枢脂肪度测量对于对印度青少年T2DM的综合风险评估至关重要.
- 仅依靠BMI可以导致在正常BMI的高流行率的人群中低诊断高血糖风险.
- 进一步的研究和临床实践应纳入中央脂肪性评估,以更好地管理印度青年T2DM.
相关概念视频
Diabetes Mellitus: Overview and Type I Subtype
4.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.8K
Diabetes: Symptoms, Diagnosis, and Complications
2.0K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.0K
Diabetes Mellitus: Type 2 and Gestational
4.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.3K
Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K
Carbohydrate Metabolism
13.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
13.7K
Obesity
1.1K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.1K


