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Updated: Jan 11, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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Published on: August 15, 2019

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剖析多基因索引对跨基因祖先的行为表型的预测准确性

Robel Alemu1,2,3, Alexander S Young2,4, Daniel J Benjamin2,4,5

  • 1Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, 415 Main St, Cambridge, 10587, MA, USA.

Research square
|November 19, 2025
PubMed
概括

在欧洲祖先上训练的多基因指数 (PGI) 在非欧洲人群中显示出预测能力降低. 诸如链接不平衡和等位基频率差异等因素有助于这种可移植性差距,因祖先和特征而异.

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